INSTITUT

FU Berlin, Fachbereich Mathematik und Informatik, Institut für Informatik

Vortrag des Informatik-Kolloquiums


Sequence comparison and evolution

Dr. Martin Vingron, Max-Planck-Institut für Molekulare Genetik, Berlin



Algorithms for the simultaneous comparison of several DNA or protein sequences tend to rely on knowledge of their evolutionary relatedness. At the same time, determining an evolutionary tree for a set of sequences generally requires a multiple alignment. This talk will suggest a heuristic approach to deal with this vicious circle. This approach sheds some light also on the role of an evolutionary tree in sequence comparison which is in turn used for designing a new algorithm for the identification of sequences related to a given family.
This is joint work, partly with Arndt von Haeseler and partly with Marc Rehmsmeier.




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